WordReference Random House Unabridged Dictionary of American English © 2026
mac•ro•nu•cle•us
(mak′rō no̅o̅′klē əs, -nyo̅o̅′-),USA pronunciation n. [Biol.]
mac′ro•nu′cle•ar, adj.
- Microbiologythe larger of the two types of nuclei occurring in ciliate protozoans, having a multiple set of chromosomes and functioning in cell metabolism and protein synthesis. Cf. micronucleus.
- Neo-Latin; see macro-, nucleus
- 1890–95
'macronucleus' also found in these entries (note: many are not synonyms or translations):