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methotrexate

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WordReference Random House Unabridged Dictionary of American English © 2025

meth•o•trex•ate n. [Pharm.]

Drugsa toxic folic acid analogue, C₂₀H₂₂N₈O₅, that inhibits cellular reproduction, used primarily in the treatment of psoriasis and certain cancers and as an immunosuppressive agent.

metho(xy)- + trexate, of unclear derivation 1950–55

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