a small hard nodular growth, which is the first diagnostic sign of acquired syphilis
WordReference Random House Unabridged Dictionary of American English © 2026
chan•cre
(shang′kər),USA pronunciation n. [Pathol.]
chan′crous, adj.
- Pathologythe initial lesion of syphilis and certain other infectious diseases, commonly a more or less distinct ulcer or sore with a hard base.
- Middle French
Latin cancrum, accusative of cancer cancer - 1595–1605
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'chancre' also found in these entries (note: many are not synonyms or translations):