any drug that neutralizes the effects of histamine, used esp in the treatment of allergies
WordReference Random House Learner's Dictionary of American English © 2026
an•ti•his•ta•mine /ˌæntiˈhɪstəˌmin, -mɪn, ˌæntaɪ-/USA pronunciation
n. [countable]
WordReference Random House Unabridged Dictionary of American English © 2026- Biochemistry, Drugsa drug that can block the action of substances in the body that cause sneezing, sniffling, or other reactions of colds and allergies.
an•ti•his•ta•mine
(an′ti his′tə mēn′, -min),USA pronunciation n. [Biochem., Pharm.]
- Biochemistry, Drugsany of certain compounds or medicines that neutralize or inhibit the effect of histamine in the body, used chiefly in the treatment of allergic disorders and colds.
- anti- + histamine 1930–35
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'antihistamine' also found in these entries (note: many are not synonyms or translations):