antidepressant

UK: /ˌæntidɪˈprɛs^ənt/

US: /ˌæntidɪˈprɛsənt, ˌæntaɪ-/

US: (an′tē di pres′ənt, an′tī-)

WordReference Random House Learner's Dictionary of American English © 2026

an•ti•de•pres•sant or an•ti-de•pres•sant/ˌæntidɪˈprɛsənt, ˌæntaɪ-/   adj. 

1. Drugs used to relieve or treat mental depression:
   antidepressant drugs.

n. [countable]

2. Drugs a drug used to treat mental depression.

WordReference Random House Unabridged Dictionary of American English © 2026

an•ti•de•pres•sant  (an′tē di pres′ənt, an′tī-), [Pharm.]
adj. 

1. Drugs of or pertaining to a substance that is used in the treatment of mood disorders, as characterized by various manic or depressive affects.

n. 

2. Drugs Also called energizer, psychic energizer. any such substance, as a tricyclic antidepressant, MAO inhibitor, or lithium.

Also, an′ti-de•pres′sant, an•ti•de•pres•sive (an′tē•di•pres′iv, an′tī-).

• anti- + depressant 1960–65

Collins Concise English Dictionary © HarperCollins Publishers::

antidepressant / ˌæntɪdɪˈprɛs^ənt/ noun

1. any of a class of drugs used to alleviate depression

adjective

1. of or relating to this class of drugs