WordReference English-Spanish Dictionary © 2025:

Principal Translations
SpanishEnglish
primero que nada loc conj (antes de empezar)first of all expr
  (formal)first and foremost expr
 Primero que nada, quisiera agradecer a todos por venir.
 First of all, I would like to thank everyone for coming.
 First and foremost, I would like to thank everyone for coming.
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'primero que nada' aparece también en las siguientes entradas:
In the Spanish description:
ante todo
English:
first and foremost


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See Google Translate's machine translation of 'primero que nada'.

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